After analyzing several cases of thrombosis after injection of the Vaxzeria vaccine, the European Medicines Agency considers these serious symptoms to be a rare consequence of vaccination with the formula developed by AstraZeneca.
A day after the statement by Marco Cavaleri, head of vaccine strategy at the European Medicines Agency (EMA), the health institution’s safety committee published his official conclusions. According to these, the clots blood, accompanied by a deficiency in platelets, should be considered a rare side effect of vaccine from AstraZeneca, Vaxzeria. This decision is based on the study of 62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic venous thrombosis (blood circulation of theabdomen), 18 of which have been shown to be fatal, reported as of March 21. Since then, the number of cases has increased: 169 cases of cerebral thrombosis and 53 cases of abdominal thrombosis were reported to EudraVigilance, which compiles the side effects for drugs authorized in Europe. As of April 4, 2021, 34 million people have been vaccinated with Vaxveria in the 27 countries of the European Union.
At the moment there is no risk factor known to thromboses, nevertheless women under 60 are the most affected by the phenomenon. Thus, the EMA recommends that healthcare professionals and vaccinees be aware that this risk, although very low, exists within two weeks of the injection. If shortness of breath, pains chest and abdominal swelling, swelling of the legs, symptoms neurological as headache Persistent or blurred vision and small red dots around the injection site, see a doctor. The EMA reaffirms that the benefit-risk balance of the Vaxzeria vaccine is still in favor of the benefits.
AstraZeneca: clear link between vaccine and thrombosis, according to EMA official
Article published on April 6, 2021 by Julie Kern
In an interview, a vaccine strategy manager at the European Medicines Agency believes that there is a clear link between AstraZeneca’s vaccine and cases of thrombosis. No official communication in this direction has yet been made.
Since its temporary suspension, the vaccine anti-Covid d’AstraZeneca (Vaxzeria) is shunned by those eligible for the vaccination, especially because side effects caused by the latter. What particularly worries the population is the appearance of thrombosis of the cerebral venous sinuses, that is to say the formation of a clot in the blood vessels that supply the blood. brain. These events mainly concern young women under the age of 50 and are accompanied by a thrombocytopenia, a quantity of platelets lower than normal values.
A link between thrombosis and vaccine established?
In his last communication on the subject, the European Medicines Agency (EMA) indicates that ” a causal link with the vaccine is not proven, but it is possible, and analyzes are continuing “. But, on April 6, 2021, Marco Cavaleri, the head of vaccine strategy at the EMA, said in the Italian daily The messenger : “We can now say it, it is clear that there is a link with the vaccine. What causes this reaction, however, we don’t yet know. An official announcement from the EMA, which has not confirmed the statements of Marco Cavaleri, should appear soon, because scientists are meeting around the question between April 6 and 9, 2021.
If, according to Marco Cavaleri, there is a link between the vaccine and thrombosis, the mechanism involved has not yet been deciphered. The association of thrombosis with thrombocytopenia, which leads to bleeding disorders, is quite unique. According to Inserm, it is linked to alterations in the immune system and has not yet been observed following vaccination. Despite these suspicions, the overall benefit / risk ratio of the Vaxzeria vaccine is still positive, but it could be re-estimated based on age. In France, the Haute Autorité de santé recommends vaccinating only people over 55 years of age with the Vaxzeria vaccine.
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