AstraZeneca: what solution for the French waiting for the second dose?

AstraZeneca: what solution for the French waiting for the second dose?
AstraZeneca: what solution for the French waiting for the second dose?
                                                            Faced with doubts about the risk of thrombosis, the AstraZeneca vaccine is now reserved for over 55s in France.  But for all younger people, first vaccinated in recent weeks with the serum, uncertainty hangs over the injection of the second dose.  The High Authority of Health is working on the possibility of falling back on Pfizer and Moderna, but the methods of administration are not decided.                         

The European Medicines Agency (EMA) recognized Wednesday April 7 "a possible link" between rare cases of thrombosis and the AstraZeneca vaccine, while ensuring that the balance benefits / risks remained "positive" in this period of pandemic. Following these announcements, Belgium has let it be known that it is now reserving injections of the Swedish-British serum to people over 55 years of age.

Italy and Spain only offer it over the age of 60. In France, the Haute Autorité de Santé has also decided to only vaccinate those over 55 years old until further notice. Problem: thousands of French people under 55 have already received a first dose of AstraZeneca in recent weeks and are waiting for the second injection.

Nearly 500,000 people affected

As recalled Europe 1, 490,000 people considered vulnerable or exercising a profession in the health field were vaccinated. They are therefore supposed to receive their booster within 9 to 12 weeks of the first dose. The president of the HAS, Dominique Le Guludec, wanted to be reassuring at the end of March by affirming: “There is no worry, we can wait the 12 weeks, or even a little more, and by then we will have the answers “.

Responses expected by the population, and in particular caregivers, some of whom were vaccinated in February. They remain in doubt, especially since it is not possible today to choose a vaccine. The French must comply with the rules enacted around injections and especially the stocks available in vaccination centers, doctors and pharmacists.

An association with messenger RNA?

The HAS is currently working on the possibility of injecting messenger RNA vaccines as a second dose, such as Pfizer or Moderna. But scientists are still unaware of the actual effectiveness of the mixture. Will it be necessary to start from scratch and administer two doses of new serum? In the United Kingdom, researchers have initiated a study on volunteers over 50, vaccinated against Covid-19 with a Pfizer / AstraZeneca combination.

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